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Hydrate. Balance. Rejuvenate.

Biome One Rejuvenating Serum

Biome One Rejuvenating Serum

A turbocharged, weightless and silky serum that transforms skin health and radiance, using our new-era super ferments and actives.

  • Intense Hydration
  • Improved skin radiance
  • Smooths texture
  • Evens and brightens
  • Skin barrier health

Targets: Early ageing, dry and dehydrated skin. 

Suitable for: All skin types, even sensitive.





Our serum has a weightless, silky texture that absorbs in an instant. It's powered by Super Ferments and actives - new-era actives that relaunch the skin’s natural power of self-regeneration and renewal. Fermented Hyaluronic Acid and prebiotic Inulin flood the skin with hydration, fortifying the skin barrier and microbiome. It also contains an antioxidant complex, which delivers potent cellular defence. Skin is left protected, strengthened and at its visibly healthiest, ageless best.

Powered by: Super Ferments & Actives

Fermented Micro-algae

Promotes cell regeneration, microbiome support

Fermented Lactococcus Lactis

Optimised skin function and renewal

Fermented Black Tea 

Improves skin radiance

Fermented Hyaluronic Acid

Intense hydration

Prebiotic Inulin

Deep skin hydration & skin barrier health

Full Ingredient List

Aqua (Water), Glycerin, Coco-Caprylate/Caprate, Borago Officinalis (Borage) Seed Oil, Lactococcus Ferment Lysate, Inulin, Squalane, Cetyl Phosphate, Saccharomyces/Xylinum/Black TEA Ferment, Sodium Hyaluronate, Chlorella Vulgaris (Plankton) Extract, Lactobacillus Ferment, Propanediol, Arginine, Sodium Stearoyl Glutamate, Maltodextrin, Xanthan Gum, Cetyl Alcohol, Anthemis Nobilis (Chamomile) Flower Oil, Sodium Chloride, Lactic Acid, Citric Acid, Hydroxyaceophenone, Sodium Levulinate, Sodium Anisate, Potassium Sorbate, Sodium Benzoate

How to apply

Use AM + PM on freshly cleansed skin. Apply one pump using upward sweeping motions. Don’t neglect your neck!

TRY: Spritz our FORTITUDE FACE MIST prior to applying your serum to maximise overall hydration and protection. 


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"love how gentle the products are and how silky they feel when applied, my skin feels really hydrated and soft.

Rose, verified reviewer


A close up headshot of a model with clear skin tilting his head to the site with shadows across the left side of his face.

Skin Benefits:

Delivers Deep Hydration

Dry skin often takes on an older appearance, displaying deeper lines and a rougher texture. We use ingredients backed by science to deliver a revolutionary twofold approach to hydration. Firstly, Fermented hyaluronic acid, a supercharged version of this humectant hero, delivers intense hydration by drawing moisture deep into the skin, restoring the plump, dewy appearance we all associate with a more youthful-looking complexion. This is partnered with a prebiotic super-hydrator, Inulin, which works by replenishing the water resevoir on the skin to fortify the skin barrier and microbiome.

Supports the Microbiome

Any skin issue you’re experiencing now – from irritation and redness to breakouts and eczema – are all likely to link back to an impaired barrier function and compromised microbiome. Our new-era formulas are powered by FutureFerments™, with the skin’s precious microbiome in mind. This regenerative, skin-quenching serum contains powerful fermented actives with prebiotic effect, that work to accelerate and improve skin renewal, skin barrier function and microbiome health.

Supports Skin Self-Regeneration and Renewal

Did you know that as we age our skin slows down, becoming drier, stretched and less resilient? But did you also know that your skin has the ability to accelerate its own self-renewal and regeneration, in effect to behave younger? Thanks to a complex of powerful FutureFerments™ our serum supports and optimises your skin’s natural regeneration and renewal, improving skin barrier function, skin health and leaving skin at its radiant, ageless best.

Streamlines your Skincare

The more science-backed actives a product contains, the less of it you need to put on your face to get results. Cultured’s sustainability ethos encourages less waste, allowing you to adopt a more streamline routine that’s better for your skin, and the planet.

Low angle shot of the Biome One Serum in front of its packaging against a white background.

Why it's Cultured.

Our weightless, results-driven formula uses powerful, new-era FutureFerments™ to deliver an immediate plumping effect, while kick-starting the skin’s own ability to self-renew, rebalance and regenerate itself. The result? Long-term skin health and ageless radiance, thanks to a restored barrier function, diverse microbiome and revitalised skin function.

Customer Reviews

Based on 38 reviews

Absolutely favourite product! Great absorption. Leaves the skin moistures and rejuvenated.

John D.
Youthful skin

I love to use this serum after the cleansing milk. It absorbs quickly and makes skin looking and feeling fresh and youthful

Lovely Serum

The consistency is thin but rich. The serum applies easily and evenly; additionally, it absorbs into the skin quickly and doesn't leave any residue and it is not sticky or greasy. Works well with or without makeup. It is effective for any day or night skincare routine as hydration is always necessary.

Rejuvenate serum

My face soaked this in straight away my it felt very smooth afterwards n doesn’t leave a sticky residue would recommend this product

Jiba S.
Lovely serum

Amazing serum with a nice texture, quick absorption, and skin feels soft, plump and healthy. Love it !

Refreshing and light

Lovely to put on after the cleanser and mask. Leaving My skin feeling fresh and light.